People

People

Dr Donald J. Davidson, MBChB PhD

Senior Research Fellow /  Senior Lecturer

Donald is a medical graduate of the University of Edinburgh who chose to pursue a scientific research career. He completed a PhD at the MRC Human Genetics Unit, studying the pathogenesis of cystic fibrosis lung disease, then was awarded a Wellcome Trust Travelling Research Fellowship to undertake post-doctoral training in innate immunity research at the University of British Columbia, Vancouver.

After four years in Canada, he was recruited to the MRC Centre for Inflammation Research at the University of Edinburgh, where he has developed an independent research group, focused on host defence peptides and innate host defence mechanisms, funded initially as a Wellcome Trust Research Career Development Fellow, and subsequently as an MRC Senior Non-clinical Fellow.

Honours & Awards
  • Elected as GRC Antimicrobial Peptides Conference Vice-Chair (2017) and Chair (2019)
  • Elected as Fellow of the Society of Biology (2015)
  • Distinguished Collaborator Award, Murdoch University, Perth, Australia, 2012-2015
  • MRC Senior Non-clinical Fellowship award, 2011 – 2016
  • Miss A.M. Urquhart’s Charitable Trust, young scientist award, 2005
  • Wellcome Trust Career Development Fellowship award, 2005
  • B.C. Research Institute “Research team of Distinction” award, 2004
  • Best poster presentation, Canadian Bacterial Diseases Network Meeting, 2003
  • B.C. Research Institute Outstanding Achievement by a Postdoctoral Fellow award, 2002
  • Canadian Cystic Fibrosis Foundation Fellowship award, 2002
  • Wellcome Trust International Travelling Prize Fellowship award, 2000
Selected Recent Invited Presentations
  • International Symposium Centred on Understanding and Preventing Infection in Children, Vancouver, Canada (2017) – “Cathelicidins have direct antiviral activity against respiratory syncytial virus in vitro and protective function in vivo
  • Pulmonology and Critical Care Medicine Conference, Nevada, USA (2017) – “Cathelicidins have direct antiviral activity against respiratory syncytial virus in vitro and protective function in vivo
  • Antimicrobial Resistance Research in Edinburgh Symposium, Edinburgh (2017) – “Antimicrobial Host Defence Peptides; potential in novel therapeutic interventions for AMR”
  • Society for Leukocyte Biology 49th Annual Meeting, Verona, Italy (2016) – “Cathelicidins have direct antiviral activity against respiratory syncytial virus in vitro and protective function in vivo in mice and humans.”
  • RegPep 2016 conference Rouen, France (2016) – Invited Session Chair & Speaker: “Antiviral function of host defence peptides against respiratory viruses.”
  • ALTANT conference Utrecht, Netherland (2016) – Keynote speaker: “Cathelicidins in host defence against bacterial and viral lung infection.”
  • Gordon Conference on Biology of Acute Respiratory Infection, Galveston, USA  (2016) Invited talk – “Cathelicidins have direct antiviral activity against respiratory syncytial virus in vitro and protective function in vivo in mice and humans.”
  • Roslin Institute, Edinburgh, Virology seminar series (2016) – “Cathelicidins: modulators of host defence against viral & bacterial lung disease”
  • Rottnest Research Meeting, Perth, Australia (2015) Invited International Speaker “Cathelicidins: protective host defence peptides with key roles in pulmonary infections”
  • Gordon Conference on Antimicrobial peptides, Italy, Invited talk (2015) – “Cathelicidins modulate innate and adaptive cellular responses at epithelial surfaces in the lung & gastrointestinal tract.”
  • Glasgow Caledonian University, Dept. of Life Sciences Bioseminar series (2015) – ” Antimicrobial peptides: modulators of inflammation in the lung and the skin”
  • BSI Summer School, Edinburgh (2014) – “Antimicrobial / host defence peptides; roles in immunology”
  • Glasgow University Immunobiology seminar series (2014) – “Cathelicidins: antimicrobial peptides with key immunomodulatory roles in pulmonary infections”
  • University of Leicester, Biology of Host Pathogen Interactions meeting (2013) – “Host defence peptides as antiviral agents in the lung”
  • Edinburgh Infectious Diseases Symposium, Edinburgh (2013) – “Host defence peptides in viral infections”
  • Gordon Conference on Antimicrobial peptides, Ventura CA (2013) – “The antiviral properties of cathelicidins against pathogenic respiratory viruses”
  • Australian Society for Immunology, Perth, Australia (2012) – “Cathelicidins as modulators of host defence: Cell death and differentiation”
  • Murdoch University, Perth, Australia (2012) Distinguished Collaborator Seminar – “Cathelicidins in pulmonary infection: antiviral and antibacterial immunomodulators”
  • University of Gießen, Germany, SFB/TRR84 Seminar Series Invited Speaker (2012) – “Cathelicidins as immunomodulatory antimicrobial agents in infectious lung diseases”
Supervisory Skills
    • Danielle Minns (c) (2017 – current) PhD student
    • Sara van Boeckel (c) (2016 – current) PhD student
    • Tina Baker (c) (2013 – 2017) PhD student – Next: Postdoc
    • Pallavi Mandal (2013 – current) PhD student
    • Bingjie Wang (2012 – 2017) MSc/PhD student – Next: Pharma
    • Emily Gwyer Findlay (2012 – 2017) Postdoc – Next: Royal Society Fellow
    • Brian McHugh (2011 – current) Postdoc
    • Silke Logermann (2011 – 2015) MSc/PhD student – Next : Postdoc
    • Ayub Qureshi (c) (2011 – 2016) MPhil student
    • Robert Gray (2008 – 2016) Intermediate Clinical Fellow – Next: Senior Fellow
    • Paula Beaumont (2007 – 2014) PhD student – Next: Medical student
    • Lorraine Frew (c) (2011 – 2014) PhD student – Next: Research Associate
    • Olga Moncayo (2013) Clinical fellow – Next: Clinician / Honorary fellow
    • Simon Bate (2011 – 2012) MSc by Research – Next: HPA Aerobiologist
    • Hsin-Ni Li (2006 – 2010) PhD student – currently Clinical Pathologist
    • Peter Barlow (2005 – 2008) Postdoc – currently Reader (Napier University)
    • Dawn Bowdish (c) (2000 – 2005) PhD student (Thesis Grade 1 distinction + Cangene Gold award for Canadian Microbiology Graduate of the Year 2005) – currently Associate Professor (McMasters Uni)
    • Karen Chu (c) (2000 – 2004) PhD student – currently Scientific Editor
    • Elaine Lau (c) (2001 – 2004) MSc student (Thesis top 10% grade) – currently Research Assistant

(c = co-supervisor)

Formal Mentoring (2013 – current): 2
MSc mini-project and maxi-project students (2011 – current): 9
Summer students and Honours students (1998 – current): 5
Managing technical staff: 2001 – current
Managing People – University of Edinburgh Transferable Skills Training course

Other responsibilities

Teaching

    • Edinburgh University Students Association Teaching Award Nominee 2012-2013 for the “Support Student learning” award
    • University of Edinburgh MBChB – Student Selected Component 2a Tutor, 2006 – 2014
    • University of Edinburgh MBChB – Course Organiser: Student Selected Component 2a, 2007 – 2013
    • University of Edinburgh MSc in Life Sciences – Lecturer, 2007 – current
    • PhD thesis examining: external (x4) & internal (x8) examiner, non-examining chair (x1)

 

Reviewing

    • Advisory board member: Inflammation Research
    • Manuscript and Grant reviewer; including Wellcome Trust, MRC, BBSRC, French National Research Agency, Medical Research Scotland, Nature Communications, Journal of Immunology, Mucosal Immunology, Journal of Leukocyte Biology, Innate Immunity, PLoSOne, Infection & Immunity, Immunology, Inflammation Research, Foundation for Polish Science.

 

Other Academic Roles

Meeting organisation
  • Elected as GRC Antimicrobial Peptides Conference Vice-Chair (2017) and Chair (2019)
  • Scientific Organising Committee: Inflammation and Disease Meeting, Manchester 2014
  • Scottish MRC Centenary Community Event Committee member, 2013
  • Scientific Organising Committee: European Macrophage and Dendritic Cell Society Annual Symposium 2010
  • Organiser of the Centre for Inflammation Research Seminar Series, 2009 – 2013
  • Queen’s Medical Research Institute Postgraduate Open Day Co-ordinator, 2007 – 2012
  • Founding member, and Principal organiser of “Inflammation in Bacterial and Viral infections” meetings series & Annual Symposia, 2007 – 2010
  • Founding member, Trainee Choice Distinguished Lectures in Medicine Series, 2003 – 2004
  • Initiation and organisation of BCRI Institute CPIC Trainee seminars, 2001 – 2004
Public Engagement / Science Communication
  • Academic Lead for Public Engagement at UoE/MRC CIR, 2015 – current
  • Chair of UoE/MRC CIR Public Engagement & Communications Committee, 2013 – current
  • CIR representative on the MRC Open Communications Forum, 2015 – current
  • UoE/MRC CIR Lead for MRC Festival of Medical Research, 2016 – current
  • Conceived and developed “Supercytes” game, animations and teachers resource 2015 – current
  • Development/delivery of activities and workshops for the Edinburgh Science Festival, 2014- 2017
  • Institute of Ideas “Debating Matters” – Qualifying rounds & Regional Finals judge (2012 – 2015)
  • Primary School Outreach events: Science week (2012-15, 2017)
  • ISSF2 project “IMPs for Inflammation” awarded funding, with “Supercytes; the immune cell standoff” and “Anatomy Squared: Lungcraft” currently under development.
  • British Society for Immunology “Going Viral” SciArt initiative (see News section), 2012
  • Secondary School work experience visitors x 3, 2011- current
  • Illustration and Development of MicroMania (see News section), 2010 – 2011
  • Invited speaker at the Wellcome Trust PhD students Career Day, 2007-2010
  • Royal Society MP-Scientist Pairing scheme participant, 2006 – 2007
  • SciArt and Scientific cartooning, including publications in Bioessays, Science, Nature Genetics, Nature Medicine, TiG, TiBS, Cold Spring Harbor Human Genome Mapping and Sequencing conferences, EUSci, MRC News, US Adult CF Association Roundtable.

Donald.Davidson@ed.ac.uk
Tel: +44 (0)131 242 6658

MRC / University of Edinburgh Centre for Inflammation Research,
Queen’s Medical Research Institute, W2.05,
47 Little France Crescent,
Edinburgh, EH16 4TJ,
Scotland, UK

Administrative Secretary: Sheila Marshall
Sheila.Marshall@ed.ac.uk
Tel: +44 (0)131 242 9484


Lab Members

Find out more about the members of the lab team

Bingjie Wang
Bingjie Wang
Bingjie Wang

PhD Student

Supervisors: Dr Donald J. Davidson, Dr Brian McHugh, Dr Richard Weller
Start Date: Oct 2013

Bingjie is a medical graduate from Peking University, registered for a 1+3 year PhD at the University of Edinburgh and funded by a China Scholarship Council/University of Edinburgh Award. Having completed her first year MSc by Research Project, she then undertook her PhD in the Davidson lab, studying host defence peptides in atopic dermatitis. Bingjie has now successfully defended her thesis and will graduate this summer

Brian McHugh
Brian McHugh

Senior Postdoctoral Researcher

Email: Brian.McHugh@ed.ac.uk
Tel: +44 (0)131 242 6661

Brian is a senior researcher with specialist expertise in molecular biology, tissue culture and imaging. His current research is focused on the immunomodulatory role of cathelicidins in the lung, with particular reference to cell death in infected cells, and the role of defensins in atopic dermatitis. Brian completed his undergraduate degree in Genetics in 1996 at Trinity College Dublin, following this with a Ph.D. at the University of Edinburgh in 2001. Since then he has undertaken postdoctoral work in the areas of cell division, cell migration, and tumour growth and metastasis in lung cancer. He was awarded a Junior Fellowship from the British Heart Foundation in 2005 and a Norman Salvesen Emphysema Research Trust Fellowship in 2008, and has been co-applicant on successful project grant applications from the Wellcome Trust, Cancer Research UK and the Chief Scientist Office in the Scottish Executive. He joined the Davidson lab in 2011.

Lauren Melrose
Lauren Melrose

Research Technician

Email: Lauren.McKendrick@ed.ac.uk

Lauren works as a Research Assistant for the Centre for Inflammation Research, including part-time support for the Davidson lab. She has a degree in Microbiology and Biotechnology from Edinburgh Napier University. She has experience of many laboratory techniques including genotyping, histology and tissue culture.

Pallavi Bedi
Pallavi Mandal
Pallavi Bedi

PhD student / Clinical Fellow

Supervisors: Prof Adam Hill, Prof Adriano Rossi & Dr Donald Davidson
Start Date: Sept 2013
Funding: Chief Scientist Office

Email: drpallavibedi@gmail.com

Following training for two years as a Specialty Registrar in Respiratory Medicine, Pallavi received two years funding from the CSO to conduct a double blinded RCT with high dose statins in non cystic fibrosis bronchiectasis. This study is now in the final stages of completion, to be submitted as an MD thesis to the University of Edinburgh by October 2013.
Pallavi’s area of interest is translational research in bronchiectasis, a condition characterized by excessive neutrophilic airways inflammation. She has been undertaking a PhD with funding from the CSO to research the role of Lipoxin A4 in bronchiectasis, with particular reference to failure in resolution of inflammation. She will be developing and utilizing ex vivo models using lung and blood derived cells from a bronchiectatic patient cohort with a view to the development of novel therapeutic strategies.

Sara van Boeckel
Sara van Boeckel

PhD Student / Clinical Fellow

Supervisors: Dr Sarah Stock, Dr Donald Davidson, Prof Jane Norman
Email: svanboe@exseed.ed.ac.uk

Start Date: Sept 2016

Sara is a medical graduate from the University of Groningen in the Netherlands. In her 6th year of medicine she worked on a 6 month master research on fetal inflammation in the context of preterm labour at the University of Edinburgh. After completing her degree and a year of clinical work in the Obstetrics and Gynaecology department of the Hospital in Enschede, the Netherlands, she has returned to the University of Edinburgh for a 3 year Clinical Research Fellowship to investigate the influence and possible therapeutic interventions of circulating cell-free fetal DNA on preterm labour.

Danielle Minns
Danielle Minns

PhD Student

Supervisors: Dr Emily Gwyer Findlay, Dr Donald Davidson
Email: s1691776@sms.ed.ac.uk

Start Date: May 2017

Danielle graduated from Royal Holloway College with a BSc (Hons) in Biomedical Sciences. She then went on to complete an MRes in Molecular and Cellular Biosciences at Imperial College London, with a particular interest in immunoregulation. After having spent a few years working as a Research Assistant on a number of different projects, Danielle is now pursuing her PhD, working on innate modifiers of T cell behaviour during inflammatory disease.

Sheila Marshall
Sheila Marshall

Administrative Secretary

Email: Sheila.Marshall@ed.ac.uk
Tel: +44 (0)131 242 9484

Sheila is administrative secretary to Dr Donald Davidson, Prof. Sarah Howie & Prof. P. Saunders.


Associated Lab Members

Find out more about the associated members of the lab team

Emily Gwyer Findlay
Emily Gwyer Findlay

Royal Society Dorothy Hodgkin Fellow

Email: emily.findlay@ed.ac.uk
Tel: +44 (0)131 242 6655

Emily is a Fellow with particular interests in immunology and in vivo models of infection. Emily has a combined BSc and Mres in biochemistry from Imperial College London and the University of Barcelona, completed in 2004. She then did a PhD at Imperial under Professor Tracy Hussell, focusing on T cell activation and development in a range of inflammatory diseases. Following this, Emily moved to the LSHTM to carry on T cell work in the malaria model, with Kevin Couper and Eleanor Riley. From 2012 she worked as a postdoctoral researcher in the Davidson Lab at the MRC Centre for Inflammation Research at the University of Edinburgh, investigating the role of cathelicidins in defence against infectious lung disease and the modulation of adaptive immune responses. In 2017 she established her own research group, with the award of a prestigious Royal Society Dorothy Hodgkin Fellowship, for her project entitled “Cathelicidin is critical for pathogenic T cell development in multiple sclerosis”, working in close collaboration with Donald Davidson.

Robert Gray
Robert Gray

NRS/Universities Scottish Senior Clinical Fellow & Honorary Consultant Respiratory Physician

Email: R.D.Gray@ed.ac.uk
Tel: +44 (0)131 242 6658

Having established his research group as a Wellcome Trust Intermediate Clinical Fellow, leading an independent programme of work within the Davidson Group, the award of a prestigious NRS/Universities Scottish Senior Clinical Fellowship in late 2016 enabled Robert to expand his research group at the MRC / University of Edinburgh Centre for Inflammation Research. His team study the role of calprotectin in inflammatory lung disease, with particular emphasis on cystic fibrosis and neutrophil NETosis, and continue to work in close collaboration with Donald Davidson.

He is also an Honorary Consultant Respiratory Physician (NHS Lothian), with a specialist interest in cystic fibrosis lung disease, and a keen and talented bagpipe player.

Key collaborators: Prof. Chris Haslett, Prof. Adriano Rossi, Dr Paul McCray Jr, Dr Thomas Vogl, The Scottish Adult CF Unit.


Alumni

Find out more about our alumni

Annie Mackellar
Annie Mackellar

Research Assistant

Annie worked as a Research Assistant from 2008 – 2015, initially directly for Donald, and then with Dr Robert Gray, before retiring. Her extensive experience in biomedical research made her the lab guru in all manner of different techniques. Annie was also responsible for the MRC / University of Edinburgh Centre for Inflammation Research Pathogenic Virus tissue culture facility.

Ayub Qreshi
Ayub Qreshi

MPhil Student

Primary Supervisors: Dr Donald J. Davidson & Dr Richard Weller
Additional Supervisors: Dr Brian McHugh
Start Date: Sept 2009

Ayub is a Dermatologist trained in Medicine at Quaid-E-Azam Medical College, Bahawalpur, Pakistan. Following research experience in Kiev University, Ukraine and Wake Forest University, North Carolina, USA, Ayub came to the University of Edinburgh. Ayub joined the Davidson lab for the later part of his degree studies and, some time afterwards, in 2016, he was awarded an MPhil, for research examining the roles of Staphylococcus aureus and cationic host defence peptides in atopic dermatitis.

Benjamin Kruczyk
Benjamin Kruczyk

MSc student

Email: s1465985@sms.ed.ac.uk

Benjamin originally studied Biological Science at the University of East Anglia. After his undergraduate degree he then studied at King’s College London, completing a Masters in Immunology, focusing on the prospective isolation of progenitors for inflammatory dendritic cells.
Benjamin completed an MSc in Science Communication and Public Engagement at the University of Edinburgh, during which time he worked on Donald Davidson’s ISSF2-funded “IMPs for Inflammation” project, helping to develop elements of the “Supercells: the inflammatory cell showdown” educational card game as part of his dissertation research project.

Emily Gwyer Findlay
Emily Gwyer Findlay

Royal Society Dorothy Hodgkin Fellow

Email: emily.findlay@ed.ac.uk
Tel: +44 (0)131 242 6655

Emily is a Fellow with particular interests in immunology and in vivo models of infection. Emily has a combined BSc and Mres in biochemistry from Imperial College London and the University of Barcelona, completed in 2004. She then did a PhD at Imperial under Professor Tracy Hussell, focusing on T cell activation and development in a range of inflammatory diseases. Following this, Emily moved to the LSHTM to carry on T cell work in the malaria model, with Kevin Couper and Eleanor Riley. From 2012 she worked as a postdoctoral researcher in the Davidson Lab at the MRC Centre for Inflammation Research at the University of Edinburgh, investigating the role of cathelicidins in defence against infectious lung disease and the modulation of adaptive immune responses. In 2017 she established her own research group, with the award of a prestigious Royal Society Dorothy Hodgkin Fellowship, for her project entitled “Cathelicidin is critical for pathogenic T cell development in multiple sclerosis”, working in close collaboration with Donald Davidson.

Greg Armstrong
Greg Armstrong

MSc Student

Primary Supervisor: Dr Donald J. Davidson
Start Date: Jan 2012
End date: April 2012
Email: gregarmstrong87@gmail.com

Greg is a MRC/University of Edinburgh Centre for Inflammation Research 4-year PhD student. He conducted his 2nd mini-project in the Davidson lab, focused on the inflammomodulatory potential of CHDP on macrophages.

Hsin-Ni Li
Hsin-Ni Li

PhD Student 2006 – 2010

Primary Supervisor: Dr Donald J. Davidson
Additional Supervisors: Prof. Adriano Rossi, Dr Peter Barlow

Email: penguin19801031@hotmail.com

Hsin-Ni is a clinician scientist with an undergraduate degree in Medicine from the National Taiwan University. She completed a PhD at the MRC / University of Edinburgh Centre for Inflammation Research, with her research focused on the capacity of antimicrobial peptides to induce secondary necrosis in neutrophils and the inflammatory consequences of this process. Her industrious approach was a great bonus in starting up the lab group and we gradually turned her a little bit Scottish, even if she never came to enjoy the lab meeting biscuit and cake-fest! Hsin-Ni is now in specialist training as a Clinical Pathologist in Taiwan.

Holly Stevens
Holly Steven

Research Assistant

After graduating with a BSc (Hons) degree in Biology from the University of Bath, Holly went on to complete an MRes at the University of Glasgow in Biomedical Sciences (Integrative Mammalian Biology) funded by the MRC. She has worked as a technician within the Centre for Neuroscience at the University of Glasgow, before joining the Davidson lab as a Research Assistant from 2015 – 2017.

 

 

 

 

Jana Ovciarikova
Ovciarikova

MSc Student

Primary Supervisor: Dr Donald J. Davidson
Co-supervisors: Dr Emily Gwyer Findlay
Dates: April – August 2013

Jana graduated from the University of Edinburgh with a degree in Immunology. During her undergraduate studies she became very interested in the various processes involved in inflammation, especially in the role of immune system. Jana studied for a Masters degree at the University of Edinburgh, conducting her second maxi-project in the Davidson lab on the role of LL-37 in the modulation of dendritic cell differentiation and function.

Kate Regan
Kate Regan

Undergraduate medical student

Supervisors: Dr Robert Gray & Dr Donald J. Davidson
Start Date: Jan 2012
Email: kateregan4@gmail.com

Kate first came to the lab as undergraduate student studying Medicine at the University of Edinburgh, to conduct the Honours project of her intercalated BSc with Dr Robert Gray. Her project, studying cell death in cystic fibrosis neutrophils, was awarded the Photometrics UK prize for the best Honours project in her Molecular Genetics Honours year group. Kate then returned to continue the work on a Summer Studentship in summer 2012 and has kept involved in various capacities ever since.

Lisa Young
Lisa Young

Research Assistant

Lisa worked in the Davidson Lab from 2014 – 2015, working as a Research Assistant, primarily with Brian McHugh and Emily Gwyer Findlay. She completed her undergraduate degree at the University of Strathclyde in 2013, achieving an upper second class BSc Honours in Biochemistry and Immunology. Following this, Lisa studied at the University of Glasgow, graduating in 2014 with an MRes with Distinction in Biomedical Sciences (Integrative Mammalian Biology). She has both practical and theoretical knowledge of many laboratory techniques including flow cytometry, genotyping and tissue culture.

Lorraine Frew
Lorraine Frew

PhD Graduate

PhD Project: The production and function of cervical antimicrobial peptides in pregnancy
Timescale: October 2010 – Jan 2014

Supervisors: Dr Sarah Stock, Professor Jane Norman and Dr Donald Davidson
Funding: Academy of Medical Sciences/Wellcome Trust, Jennifer Brown Research Laboratory

Following an undergraduate degree and MSc by research in Reproductive Biology at the University of Edinburgh, Lorraine studied for a PhD in the MRC Centre for Reproductive Health, in collaboration with the MRC Centre for Inflammation Research, University of Edinburgh. Lorraine researched the production and function of cervical antimicrobial peptides (AMPs) in pregnancy, with a particular interest in their significance in preterm labour. Preterm labour is a common pregnancy problem, which is associated with increased death and disability in babies and mothers. We believe that AMPs may be important in the pathophysiology of preterm membrane rupture and spontaneous preterm labour and that they make attractive targets for treatments to prevent preterm birth. Lorraine graduated with her PhD in 2014, before working as a Research Laboratory Associate at the Centre for Human Reproductive Science, Birmingham

Olga L. Moncayo
Olga L. Moncayo
Olga L. Moncayo

Clinical Lecturer

Email: omoncayo@staffmail.ed.ac.uk

Olga is a Clinical Lecturer and Honorary Specialist Registrar in Medical Microbiology. She has special interests in the dynamics of bacterial colonisation in humans and in the recognition of the early processes that precede the development of invasive infection, particularly in relation to Methicillin-resistant Staphylococcus aureus and hospital acquired pneumonia. Olga spent six months undertaking an Out of Programme Research experience with the Davidson group.

Paula Beaumont
Paula Beaumont

PhD Student

Primary Supervisor: Dr Donald J. Davidson
Additional Supervisors: Prof. John R. W. Govan
Dates: Sept 2007 – Oct 2014

Following a Medical Microbiology Honours degree and Masters by Research at the University of Edinburgh, Paula studied for a PhD in the MRC / University of Edinburgh Centre for Inflammation Research. Paula researched the host defence activities of cathelicidins in bacterial pulmonary infection, with particular reference to peptide expression in disease, peptide-induced cell death, and immunomodulatory anti-pseudomonal properties. Paula left to take up an undergraduate degree in Medicine, but later wrote up her PhD thesis – completed in 2014.

Peter Barlow
Peter Barlow

Postdoctoral Researcher 2005- 2009

Email: p.barlow@napier.ac.uk

Peter was the first member of the Davidson Lab. Following a BSc and PhD at Edinburgh Napier University, Peter worked as a postdoctoral researcher at the MRC / University of Edinburgh Centre for Inflammation Research, studying the capacity of cathelicidins in induce cell death in infected airway epithelial cells. His steadying influence and reliable approach were indispensible and his work set the basis for much of what has followed. Peter then moved to the United States, where he worked within the Influenza Division of the US Centers for Disease Control and Prevention in Atlanta, Georgia, before setting up his own lab at Edinburgh Napier University.

Rebekah Kells
Rebekah Kells

 

MSc Student

Primary Supervisor: Dr Donald J. Davidson
Co-supervisors: Dr Brian McHugh
Dates: Oct 2012 – March 2013

Email: R.Morgan-11@sms.ed.ac.uk

Rebekah is a graduate in Molecular Biology from University of Aberdeen. During her studies there she had the opportunity to work in industry for a year with ImmunoSolv which led to being awarded an undergraduate masters, M.Sci. Rebekah then joined the 1+3 year PhD programme at the University of Edinburgh, funded by Medical Research Council. She worked in the Davidson lab for her first maxi-project, characterising CHDP-induced cell death.

Robert Gray
Robert Gray

NRS/Universities Scottish Senior Clinical Fellow & Honorary Consultant Respiratory Physician

Email: R.D.Gray@ed.ac.uk
Tel: +44 (0)131 242 6658

Having established his research group as a Wellcome Trust Intermediate Clinical Fellow, leading an independent programme of work within the Davidson Group, the award of a prestigious NRS/Universities Scottish Senior Clinical Fellowship in late 2016 enabled Robert to expand his research group at the MRC / University of Edinburgh Centre for Inflammation Research. His team study the role of calprotectin in inflammatory lung disease, with particular emphasis on cystic fibrosis and neutrophil NETosis, and continue to work in close collaboration with Donald Davidson.

He is also an Honorary Consultant Respiratory Physician (NHS Lothian), with a specialist interest in cystic fibrosis lung disease, and a keen and talented bagpipe player.

Key collaborators: Prof. Chris Haslett, Prof. Adriano Rossi, Dr Paul McCray Jr, Dr Thomas Vogl, The Scottish Adult CF Unit.

Rongling Wang
Rongling Wang

MSc Biomedical Sciences student

Primary Supervisor: Dr Donald J. Davidson
Co-supervisor: Dr Brian McHugh

Rongling is a graduate of Beijing University of Chinese Medicine, with an undergraduate major in Pharmaceutical Engineering. She joined the Davidson lab to conduct a maxi-project with Dr Brian McHugh as a component of her MSc by Research in Biomedical sciences at the University of Edinburgh from Oct 2015 – March 2016.

Ross Mills
Ross Mills

MSc Student

Primary Supervisor: Dr Robert Gray
Co-supervisors: Dr Donald J. Davidson
Dates: Oct 2012 – March 2013
Email: S1259578@sms.ed.ac.uk

Ross is a graduate of Newcastle University, where he studied Medical Microbiology and Immunology, before becoming a University of Edinburgh / MRC Centre for Inflammation Research 1+3 year PhD student. He conducted his first MSc Maxi project with Dr Robert Gray, studying neutrophil cell death.

Silke Currie
Silke Currie

PhD Student

Start Date: Oct 2011
Primary Supervisor: Dr Donald J. Davidson
Additional Supervisors: Prof. Jürgen Schwarze,
Dr Emily Gwyer Findlay & Dr Paul Fitch

Following an undergraduate degree in Bioscience at the Westphalian Wilhelms University Muenster, and Masters Degrees at both the University of Edinburgh (Biomedical Sciences) and the Westphalian Wilhelms University Muenster (Bioscience), Silke studied for a PhD in the MRC / University of Edinburgh Centre for Inflammation Research, researching the anti-viral activity of cathelicidins against Respiratory Syncytial Virus. She was also Editor in chief of the University of Edinburgh science magazine EuSci. Following her PhD Silke accepted a postdoctoral position at the Max Planck Institute for Molecular Biomedicine in Münster.


Collaborators

Find out more about our collaborators

Adam Hill
Prof Adam Hill

Adam is a Consultant Respiratory Physician and Honorary Senior Lecturer at the University of Edinburgh.

Adam’s lab

Collaboration on inflammation in non-CF bronchiectasis.

Adriano Rossi
Adriano Rossi

Adriano holds the chair of Respiratory and Inflammation Pharmacology at the MRC / University of Edinburgh Centre for Inflammation Research.

Adriano’s lab

Collaboration on the roles of neutrophils in lung disease and the resolution of inflammation.

Allan Mowat
Allan Mowat

Allan is Professor of Mucosal Immunology, at the School of Life Sciences, University of Glasgow.

Allan Mowat’s lab

Collaboration on HDP and the intestinal adaptive immune system.

Andrew Currie
Dr Andrew Currie

Andrew is a BrightSpark Research Fellow and Senior Lecturer in Immunology at Murdoch University, Perth, Australia.

Andrew’s Lab

Collaboration on HDP expression and function in neonates.

Benjamin Marsland
Ben Marsland

Ben is a is an internationally recognised immunologist with expertise in infectious and inflammatory disease models and the impact of microbiome of pulmonary disease, based at University Hospital of Lausanne .

Ben’s Lab

Collaboration on microbiome and diet in pulmonary viral infection.

Chris Chiu
Chris Chiu

Chris is a Clinical Senior Lecturer and Honorary Consultant in the Department of Infectious Diseases, Imperial College London. His research interests focus mainly on B and T cell immunity to recurrent viral infections, including respiratory syncytial virus (RSV), influenza and herpesviruses, with a particular emphasis on the development of better vaccines

Chris’ Lab

Collaboration on HDP expression in RSV infection.

Dave Clarke
Dave Clarke

Dave is a Chancellor’s Fellow working in Biomolecular Mass Spectrometry at the University of Edinburgh.

Dave’s lab 

Collaboration on the chemistry and MS quantification of HDP

Dawn Bowdish
Dawn Bowdish

Dawn is an Associate Professor at McMaster University, Canada.

Dawn Bowdish’s lab

Collaboration on CHDP and the microbiome, and aging of the innate immune system.

Dominic Campopiano
Dominic Campopiano

Dom is a Professor in Organic Chemistry at the University of Edinburgh.

Dom’s lab 

Collaboration on the chemistry of CHDP

Guðmundur H. Guðmundsson
Guðmundur H. Guðmundsson

Guðmundur is a Professor at the University of Iceland, with long standing expertise in Host Defence Peptides, particularly cathelicidins.

Guðmundur’s lab

Collaboration on approaches to cathelicidin induction.

James Boardman
James Boardman

James is a Reader & Honorary Consultant in neonatal medicine at the University of Edinburgh, Scientific Director of the Jennifer Brown Research Laboratory, and Chief Investigator for the Theirworld Edinburgh Birth Cohort.

James’ Lab

Collaboration on HDP expression in neonates.

John Savill
Prof Sir John Savill

John is the Head of the College of Medicine and Veterinary Medicine at the University of Edinburgh and a PI colleague within the MRC Centre for Inflammation Research.

John’s Lab

Collaboration on CHDP-mediated modulation of dendritic cell function.

John Govan
John Govan

John holds the chair of Microbial Pathogenesis at the University of Edinburgh.

Collaboration on the microbiology of Pseudomonas aeruginosa and Burkholderia cepacia, and lung disease in cystic fibrosis.

Julia Dorin
Julia Dorin

Julia is a principal investigator at the MRC Centre for Inflammation Research, Edinburgh, and was one of Donald’s PhD supervisors.

Julia Dorin’s lab

Collaboration on the role of CHDP in innate immune signalling.

Jürgen Schwarze
Jürgen Schwarze

Jürgen holds the Edward Clark Chair of Child Life and Health at the University of Edinburgh, and is based at the MRC / University of Edinburgh Centre for Inflammation Research.

Jürgen’s Lab

Collaboration on HDP as antiviral agents in Respiratory Syncytial Virus infections.

Marc Vendrell
Marc Vendrell

Marc is a Chemist working in Biology and Optical Imaging at the MRC Centre for Inflammation Research at the University of Edinburgh. His lab studies dynamic activatable fluorophores for real-time imaging of key molecular events in cancer and inflammation.

Marc’s Lab

Collaboration on synthesis of HDP derivative and novel peptide mimics.

Nick Colegrave
Nick Colegrave

Nick is a Professor in Biology, working in Evolutionary Ecology and Social Evolution at the Ashworth Laboratories, University of Edinburgh.

Nick Colegrave’s lab

Collaboration in the development of in vivo experimental design and statistics.

Richard Weller
Richard Weller

Richard is a Senior Lecturer in Dermatology at the University of Edinburgh.

Collaboration on the role of HDP in atopic dermatological pathology.

Ross Fitzgerald
Ross Fitzgerald

Ross is based in the Laboratory for Bacterial Evolution and Pathogenesis, Centre for Infectious Diseases, University of Edinburgh, Easter Bush.

Ross’s lab

Collaboration on the microbiology of Staphyloccus aureus.

Sarah Stock
Sarah Stock

Sarah is a Clinical Lecturer and subspecialty trainee in maternal fetal medicine, at the MRC Centre for Reproductive Health, University of Edinburgh.

Sarah’s Lab

Collaboration on the role of HDP in the female reproductive tract and roles in premature labour.

Simon Milling
Simon Milling

Simon is a Reader in Immunology, at the School of Life Science, University of Glasgow.

Simon Milling’s lab

Collaboration on CHDP and the intestinal adaptive immune system.

Trevor Hansel
Trevor Hansel

Trevor is a Reader in Respiratory Clinical Pharmacology at the Faculty of MedicineNational Heart & Lung Institute, Imperial College London, Medical Director of the Imperial Clinical Respiratory Research Unit (ICRRU) at St Mary’s Hospital, and an Honorary Consultant Immunologist at St. Mary’s Hospital in London.

Trevor has a specialist interest in phase II clinical testing of new anti-inflammatory therapies for asthma and COPD, and particular expertise working on novel non-invasive methods to sample the airways: using synthetic absorptive matrices to measure cytokines and chemokines in nasal and bronchial mucosal lining fluid.

Trevor’s lab

Collaboration on non-invasive sampling of airway lining fluid.