Cathelicidin and Th17 paper out

Cathelicidin and Th17 paper out

NEW PAPER

Our latest paper, from Danielle Minns, together with Emily Gwyer Findlay’s research team, is now published in Nature Communications, freely available.

link to paper

This research suggests that the release of cathelicidin by neutrophils is required for maximal Th17 differentiation and IL-17 production by CD4+ T cells, and that this is one method by which early neutrophilia directs subsequent adaptive immune responses.

In the week of publication, our paper is in the Altmetric 97th percentile (ranked 4,503rd) of the 148,037 tracked articles of a similar age in all journals and the 99th percentile (ranked 1st) of the 15 tracked articles of a similar age in Nature Communications. Worth a read!

The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation

Minns, D., Smith, K. J., Alessandrini, V., Hardisty, G., Melrose, L., Jackson-Jones, L., MacDonald, A. S., Davidson, D. J., Gwyer Findlay, E.

Nat Commun 12, 1285 (2021).

https://doi.org/10.1038/s41467-021-21533-5

 

Davidson lab supported by funding from: Medical Research Council