Davidson & Rolfe (2001) Mouse models of cystic fibrosis. Trends in Genetics 17; S29-S37

Mouse models of cystic fibrosis.

Davidson, D. J., and Rolfe, M.
Trends in Genetics (2001) 17; S29-S37     PubMed

The development of mouse models for cystic fibrosis has provided the opportunity to dissect disease pathogenesis, correlate genotype and phenotype, study disease-modifying genes and develop novel therapeutics. This review discusses the successes and the challenges encountered in characterizing and optimizing these models. PMID:11585674
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