Animal models of Cystic Fibrosis.
Scholte, B., Davidson, D. J., Wilke, M. and De Jonge, H.
J. Cystic Fibrosis (2004) 3S2; 183-190 PubMed
Animal models of cystic fibrosis, in particular several different mutant mouse strains obtained by homologous recombination, have contributed considerably to our understanding of CF pathology. In this review, we describe and compare the main phenotypic features of these models. Recent and possible future developments in this field are discussed. PMID:15463956