Welcome to the Davidson Group
This is the personal website of Prof. Donald J. Davidson, highlighting research and engagement activities. For Professor Davidson’s professional website within the University of Edinburgh, please see the Centre for Inflammation Research.
View Professor D.J. Davidson’s profile on the Centre for Inflammation Research website
What is our Research Focus?
Our research focuses on understanding the physiological importance of host defence peptides to our ability to combat bacterial and viral infections. In addition, we study the potential of host defence peptides in the development of novel therapeutic approaches, with the potential to circumvent problems of microbial resistance to conventional treatments by enhancing natural defences.
We focus on the role of host defence peptides (HDP; also known as antimicrobial peptides) as modulators of inflammation, immunity and cell differentiation & death in infectious and inflammatory diseases. We have particular interest in diseases of the lungs (including infections with RSV and influenza, and cystic fibrosis) and the skin (including atopic dermatitis), as well as novel approaches to cancer immunotherapy and extending our knowledge of inflammatory processes to the development of novel therapeutics.
Donald J. Davidson is a medical graduate of the University of Edinburgh who chose to pursue a scientific research career. He completed a PhD at the MRC Human Genetics Unit, studying the pathogenesis of cystic fibrosis lung disease, then was awarded a Wellcome Trust Travelling Research Fellowship to undertake post-doctoral training in innate immunity research at the University of British Columbia, Vancouver. After four years in Canada, he was recruited to the MRC / University of Edinburgh Centre for Inflammation Research, where he has developed an independent research group, focused on host defence peptides and pulmonary innate defence mechanisms, funded as a Wellcome Trust Research Career Development Fellow, and subsequently as an MRC Senior Non-clinical Fellow, before being awarded the personal Chair of Host Defence and Inflammation Biology.
University of Edinburgh Centre for Inflammation Research
The group is part of the University of Edinburgh Centre for Inflammation Research; a multidisciplinary centre established in 1999 to bring together a critical mass of internationally outstanding researchers in inflammation, harnessing the skills of basic and clinical scientists to conduct internationally competitive research on the roles of inflammation in health and disease, in order to develop new approaches toward diagnosis, prevention and treatment.