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Welcome to the Davidson Group

This is the personal website of Prof. Donald J. Davidson, highlighting research and engagement activities. For Professor Davidson’s professional website within the University of Edinburgh, please see the Centre for Inflammation Research.
View Professor D.J. Davidson’s profile on the Centre for Inflammation Research website

What is our Research Focus?

Our research focuses on understanding the physiological importance of host defence peptides to our ability to combat bacterial and viral infections. In addition, we study the potential of host defence peptides in the development of novel therapeutic approaches, with the potential to circumvent problems of microbial resistance to conventional treatments by enhancing natural defences.

What is our Research Group Ethos?

In 2020 our research team worked together to create a statement detailing the group’s responsibilities and expectations, which we hope all future members of the team will also use as a guiding framework.

View the Davidson Group Ethos Statement

Research

Find out about our research

Publications

See our group’s recent research publications

Information for the Public

Get closer to our work

RESEARCH FOCUS

We focus on the role of host defence peptides (HDP; also known as antimicrobial peptides) as modulators of inflammation, immunity and cell differentiation & death in infectious and inflammatory diseases. We have particular interest in diseases of the lungs (including infections with RSV and influenza, and cystic fibrosis) and the skin (including atopic dermatitis), as well as novel approaches to cancer immunotherapy and extending our knowledge of inflammatory processes to the development of novel therapeutics.

NEWS

Cystic Fibrosis Inflammation Review out

NEW REVIEW ARTICLE Our latest review article, from Jonny Gillan, together with Robert Gray, is now out in the European Respiratory Journal link to paper This review discusses the merits of targeting inflammation in cystic fibrosis, in the context of…
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Research Group Ethos

What is our Research Group Ethos? In 2020 our research team worked together to create a statement detailing the group’s responsibilities and expectations, which we hope all future members of the team will also use as a guiding framework. View…
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Welcome Sofia & Patrick!

NEW GROUP MEMBERS Welcome to Sofia Sintoris, who has joined the Davidson group as a PhD student on the new Medical Sciences & Translational Research PhD with integrated studies in Engagement for Impact Programme, and to Patrick Lennard, who has…
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PhD viva successes

PhD VIVA SUCCESSES Danielle Minns and Sara van Boeckel both successfully completed their PhD vivas with lockdown online formats. Many congratulations to both students, and to their primary supervisors Emily Gwyer Findlay and Sarah Stock (respectively). It has been a…
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@NMfromUManitoba: Wonderful paper on effect of LL-37 #HostDefencePeptide #Cathelicidin on Th17 differentiation and related mechanisms. The range of LL-37 mediated #Immunomodulation continues to expand. Congratulations @GwyerFindlay and colleagues @djdavidsonlab https://t.co/pM7tdreR7h
@djdavidsonlab
Great to see this paper on our collaboration with @GwyerFindlay lab out, showing how a #neutrophil #Antimicrobial #HostDefencePeptide can significantly modulate the nature of immune responses https://t.co/WMxw3Zj79S
@djdavidsonlab
@BenJMarsland: Know your Tuft’s from your ionocytes? Your club from your basal? Nice review just out by @TomaszWypych8 @MucosalImmunol with the latest on the complexity and roles of cells lining the airways. Fast way to catch up on the current state-of-the-art https://t.co/19sGc3y1gJ @CCSMonash https://t.co/g32KVJRX0M
@djdavidsonlab
@bbcideas: “Vaccines are likely the most important public health intervention of the last 100 years. They've saved over a billion lives.” (Made in partnership with @RoyalSociety.) https://t.co/uxGoLR2EEl
@djdavidsonlab
@britsocimm: A new preprint study from #EAVEII suggests a substantial reduction in the risk of #COVID19 hospitalisations in Scotland after the 1st dose of Pfizer/BioNTech & Oxford/AstraZeneca #vaccines Read the response from our President, Prof @AkbarArne 👉https://t.co/QCPtEOFyQV https://t.co/3lNJv9KgHk
@djdavidsonlab

Donald J. Davidson is a medical graduate of the University of Edinburgh who chose to pursue a scientific research career. He completed a PhD at the MRC Human Genetics Unit, studying the pathogenesis of cystic fibrosis lung disease, then was awarded a Wellcome Trust Travelling Research Fellowship to undertake post-doctoral training in innate immunity research at the University of British Columbia, Vancouver. After four years in Canada, he was recruited to the MRC / University of Edinburgh Centre for Inflammation Research, where he has developed an independent research group, focused on host defence peptides and pulmonary innate defence mechanisms, funded as a Wellcome Trust Research Career Development Fellow, and subsequently as an MRC Senior Non-clinical Fellow, before being awarded the personal Chair of Host Defence and Inflammation Biology.


Lab Members

Lauren Melrose

Lauren Melrose

Research Technician

Jamil Jubrail

Jamil Jubrail

Postdoctoral Researcher

Jenny Shelley

Jenny Shelley

PhD Student

Sam Walker

Sam Walker

PhD student

SOFIA SINTORIS

SOFIA SINTORIS

PhD Student

University of Edinburgh Centre for Inflammation Research

The group is part of the University of Edinburgh Centre for Inflammation Research; a multidisciplinary centre established in 1999 to bring together a critical mass of internationally outstanding researchers in inflammation, harnessing the skills of basic and clinical scientists to conduct internationally competitive research on the roles of inflammation in health and disease, in order to develop new approaches toward diagnosis, prevention and treatment.