Home

Welcome to the Davidson Group

Our research focuses on understanding the physiological importance of host defence peptides (HDP) to our ability to combat bacterial and viral infections. In addition, we study the potential of HDP in the development of novel therapeutic approaches, with the potential to circumvent problems of microbial resistance to conventional treatments by enhancing natural defences.

Research

Find out about our research

Publications

See our group’s recent research publications

Information for the Public

Get closer to our work

RESEARCH FOCUS

We focus on the role of host defence peptides (HDP; also known as antimicrobial peptides) as modulators of inflammation, immunity and cell differentiation & death in infectious and inflammatory diseases. We have particular interest in diseases of the lungs (including infections with RSV and influenza, and cystic fibrosis) and the skin (including atopic dermatitis), as well as novel approaches to cancer immunotherapy and extending our knowledge of inflammatory processes to the development of novel therapeutics.

NEWS

RSV animation by Yee Hwee Ong

PROJECT ANIMATION MSc student Yee Hwee Ong made a video about her MSC by Research project in the lab. Watch it here:
Read Morearrow_forward

Host Defence Peptides review out

NEW REVIEW Our latest review article, on Antimicrobial Host Defence Peptides, written with my co-Chair and co-Vice Chairs from the 2019 Gordon Research Conference on Antimicrobial Peptides, is now out in Nature Reviews Drug Discovery. Freely accessible version link This…
Read Morearrow_forward

Placental inflammation paper out

NEW PAPER Our latest paper, from Sara van Boeckel, together with Sarah Stock’s research teams, is now out in Placenta, available fully Open Access. link to paper This research suggests that placental inflammation does not increase release of cell free…
Read Morearrow_forward

Supercytes visit the National Museum of Scotland

January 2020 – Donald J. Davidson shows teachers how to use card game Supercytes to teach pupils about immunology The Supercytes workshop was run in conjunction with the current ‘Parasites: Battle for Survival’ exhibition at the National Museum of Scotland. Primary,…
Read Morearrow_forward
RT @NIHRresearch: We're funding research collecting samples and data from #COVID19 patients in the UK to answer urgent questions about the…
@djdavidsonlab
Caution about using antibody tests for diagnostic purposes https://t.co/7XSpCLeld5
@djdavidsonlab
RT @edin_EID: All the talks from the Edinburgh Coronavirus workshop on Wednesday are now available - listen here! https://t.co/JY7IhozYTG
@djdavidsonlab
RT @JeremyFarrar: Amazing news - Science is our best Exit Strategy @ChanZuckerberg commits $25 million to accelerate the development of tre…
@djdavidsonlab
RT @curexcomplex: Because they implemented the measures that science showed would reduce deaths and keep the NHS operating. The report has…
@djdavidsonlab

Donald J. Davidson is a medical graduate of the University of Edinburgh who chose to pursue a scientific research career. He completed a PhD at the MRC Human Genetics Unit, studying the pathogenesis of cystic fibrosis lung disease, then was awarded a Wellcome Trust Travelling Research Fellowship to undertake post-doctoral training in innate immunity research at the University of British Columbia, Vancouver. After four years in Canada, he was recruited to the MRC / University of Edinburgh Centre for Inflammation Research, where he has developed an independent research group, focused on host defence peptides and pulmonary innate defence mechanisms, funded as a Wellcome Trust Research Career Development Fellow, and subsequently as an MRC Senior Non-clinical Fellow, before being awarded the personal Chair of Host Defence and Inflammation Biology.


Lab Members

Lauren Melrose

Lauren Melrose

Research Technician

Jamil Jubrail

Jamil Jubrail

Postdoctoral Researcher

Jenny Shelley

Jenny Shelley

PhD Student

Sam Walker

Sam Walker

PhD student

SARA VAN BOECKEL

SARA VAN BOECKEL

PhD Student

ALICIA RUIZ RODRIGUEZ

ALICIA RUIZ RODRIGUEZ

Postdoctoral Researcher

University of Edinburgh Centre for Inflammation Research

The group is part of the University of Edinburgh Centre for Inflammation Research; a multidisciplinary centre established in 1999 to bring together a critical mass of internationally outstanding researchers in inflammation, harnessing the skills of basic and clinical scientists to conduct internationally competitive research on the roles of inflammation in health and disease, in order to develop new approaches toward diagnosis, prevention and treatment.