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Welcome to the Davidson Group

Our research focuses on understanding the physiological importance of host defence peptides (HDP) to our ability to combat bacterial and viral infections. In addition, we study the potential of HDP in the development of novel therapeutic approaches, with the potential to circumvent problems of microbial resistance to conventional treatments by enhancing natural defences.

Research

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Publications

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Information for the Public

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RESEARCH FOCUS

We focus on the role of host defence peptides (HDP; also known as antimicrobial peptides) as modulators of inflammation, immunity and cell differentiation & death in infectious and inflammatory diseases. We have particular interest in diseases of the lungs (including infections with RSV and influenza, and cystic fibrosis) and the skin (including atopic dermatitis), as well as novel approaches to cancer immunotherapy and extending our knowledge of inflammatory processes to the development of novel therapeutics.

NEWS

1st prize poster award for Sam Walker

1st Prize Poster award for Sam Walker Congratulations to Sam Walker winning first prize for her poster at the Analytical Science Network 2019 meeting! “Comparing Methods to Functionalise Gold Nanoparticles with the Antimicrobial Peptide, LL-37.” Samantha Walker, Donald Davidson, Duncan…
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DC immunotherapy paper out

NEW PAPER Our latest paper is now out in OncoImmunology, available fully Open Access for you or read or listen to at: link to paper Immunotherapies are a set of new approaches being developed to treat cancer. These can work…
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Cathelicidin "fire alarm" paper out

NEW PAPER Our latest paper is now out in PLoS Pathogens, available fully Open Access for everybody to read. Lung infections are a very common cause of death worldwide. As the threat of antibiotic-resistance grows, new approaches are urgently needed…
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Chief Scientist Office Grant started

Chief Scientist Office grant We are delighted to be starting research funded by a new grant from the Chief Scientist Office today. This award will fund a new Postdoctoral Researcher (starting later in the year) and Research Assistant (Lauren Melrose),…
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Our new paper with @sarahjestock @DorinJulia @_bakertina @NormanJaneE Sara van Boeckel Lenka Hrabalkova and collea… https://t.co/a9EG5Os5fH
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RT @britsocimm: Our statement from our CEO @dougbrown_1 in response to @PHE_uk call for people to take up the MMR vaccination against measl…
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RT @mbeisen: @edyong209 @TommDoggPhD "I would request that nobody from the UK review my paper as I can never tell whether they liked it or…
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RT @MicrobesInfect: How The Philippines Is Fighting One Of The World's Worst Measles Outbreaks. The country's #measlesoutbreak has been pa…
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RT @bsicongress: We have an excellent 4-day programme of cutting edge research planned for #BSI19 Congress! Opening with our keynote Doreen…
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Donald J. Davidson is a medical graduate of the University of Edinburgh who chose to pursue a scientific research career. He completed a PhD at the MRC Human Genetics Unit, studying the pathogenesis of cystic fibrosis lung disease, then was awarded a Wellcome Trust Travelling Research Fellowship to undertake post-doctoral training in innate immunity research at the University of British Columbia, Vancouver. After four years in Canada, he was recruited to the MRC / University of Edinburgh Centre for Inflammation Research, where he has developed an independent research group, focused on host defence peptides and pulmonary innate defence mechanisms, funded as a Wellcome Trust Research Career Development Fellow, and subsequently as an MRC Senior Non-clinical Fellow.

Lab Members

Jamil Jubrail

Jamil Jubrail

Postdoctoral Researcher

Lauren Melrose

Lauren Melrose

Research Technician

SARA VAN BOECKEL

SARA VAN BOECKEL

PhD Student

JONATHAN GILLAN

JONATHAN GILLAN

PhD Student

Sam Walker

Sam Walker

PhD student

Jenny Shelley

Jenny Shelley

PhD Student

University of Edinburgh Centre for Inflammation Research

The group is part of the University of Edinburgh Centre for Inflammation Research; a multidisciplinary centre established in 1999 to bring together a critical mass of internationally outstanding researchers in inflammation, harnessing the skills of basic and clinical scientists to conduct internationally competitive research on the roles of inflammation in health and disease, in order to develop new approaches toward diagnosis, prevention and treatment.